No. StarTech.com drive duplicators perform a sector-by-sector copy, which means that the target drive must have the same sector size as the drive that is being copied. Source and destination drives must also have the same logical and physical sector size. This means 512n (512 native) and 512e (512 emulated) drives cannot be duplicated to 4Kn (4K native) drives, or vice versa.
Note: An exception to this guideline is that 512n (512 native) drives can be duplicated to 512e (512 emulated) drives, or vice versa, because the logical sector sizes are the same.